| NAME ▲ | ▼ | VESSEL ▲ | ▼ | RIG | YEAR ▲ | ▼ | AGE | MORE |
|
| Isaac Sayre | Aeronaut | Ship | 1831 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Aeronaut | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Master | | | |
|
| Isaac Sayre | Commodore Perry | Ship | 1829 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Commodore Perry | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | Sag Harbor | Master | | | |
|
| Isaac Sayre | Jones | Ship | 1826 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Jones | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | Long Island, NY | | | | |
|
| Isaac Sayre | Jones | Ship | 1828 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Jones | Ship | | 0' 0" | | | | Hair | Eye | Residence | Rank | Remarks | | | | Sag Harbor | Master | | | |
|
| Isaac Scott | Ospray | Brig | 1834 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Ospray | Brig | | 5' 11" | Black | | | Hair | Eye | Residence | Rank | Remarks | | Black Negro | | Philadelphia | | | | |
|
| Isaac Seaman | Jeannette | Ship | 1842 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Jeannette | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Greenhand | | | |
|
| Isaac Sekin | Charles | Ship | 1904 | 21 | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Charles | Ship | 21 | 5' 7 3/4" | light | | | Hair | Eye | Residence | Rank | Remarks | | light | | New Bedford | | Returned | | |
|
| Isaac Selby | Antelope | Bark | 1860 | 21 | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Antelope | Bark | 21 | | Dark | | | Hair | Eye | Residence | Rank | Remarks | | Dark | | Rouse Point Ny | | | | |
|
| Isaac Seman | Hercules | Ship | 1842 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Hercules | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Seaman | ON AT MAUI SANDWICH ISLAND 09/17/1844 | | |
|
| Isaac Shell | Gideon Howland | Ship | 1842 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Gideon Howland | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Ordinary | | | |
|
| Isaac Shepard | Maine | Ship | 1829 | 24 | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Maine | Ship | 24 | 5' 8 1/4" | Dark | | | Hair | Eye | Residence | Rank | Remarks | | Dark | | Charlestown | | | | |
|
| Isaac Shepherd | Galatea | Ship | 1828 | 23 | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Galatea | Ship | 23 | 5' 8 1/4" | Dark | | | Hair | Eye | Residence | Rank | Remarks | | Dark | | New Bedford | | | | |
|
| Isaac Sherwood | Nile | Ship | 1833 | 48 | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Nile | Ship | 48 | | Dark | | | Hair | Eye | Residence | Rank | Remarks | | Colored | | Talbot County | | DESERTED AT VALPARAISO 01/1834 | | |
|
| Isaac Simmons | Mexico | Brig | 1841 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | Mexico | Brig | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Shipkeeper | | | |
|
| Isaac Simmons | St. George | Ship | 1845 | | ⊕ |
| | | Vessel | Rig | Age | Height | Skin | | St. George | Ship | | | | | | Hair | Eye | Residence | Rank | Remarks | | | | | Boatsteerer | | | |
|
